Conducting research in collaboration with or supported by the Department of War (DoW) presents distinct ethical, regulatory, and operational considerations, especially when recruiting DoW affiliated personnel. This session features perspectives from DoW human research protection professionals and examines how DoW-specific requirements intersect with institutional responsibilities, federal regulations, and ethical principles. Attendees will gain practical insight into DoW oversight structures, approval pathways, and strategies for facilitating compliant and efficient research review while maintaining appropriate protections for human subjects.